Miltenyi, 130-106-234, CD111 Antibody, anti-human, Vio® Bright FITC

Name: CD111 Antibody, anti-human, Vio® Bright FITC
Brand: Miltenyi
SKU: 130-106-234

Size:100 tests in 1 mL, HL60 cells were stained with CD111 antibodies conjugatedor with the corresponding isotype control antibodies (left peak) and analyzed by flow cytometry using the MACSQuant® Analyzer. Cell debris and dead cells were excluded from the analysis based on scatter signals and propidium iodide or DAPI fluorescence as in the case of tandem-conjugates.

Catalog Number: 130-106-234

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Category

Mouse Isotype Controls

Pack Size100 tests

TagsMACS Antibodies Hybridomas

Description

Overview
Clone R1.302 recognizes the CD111 antigen, a 75 kDa type I transmembrane glycoprotein also known as poliovirus receptor related 1 protein (PRR1), PVRL1, HveC, and Nectin-1. Nectins are involved in the formation of the mechanical adhesive puncta adherentia junctions of synapses. CD111 is an adhesion molecule that can be found in a wide range of tissues where it localizes in various junctions such as the adherens junction of epithelial tissue or the chemical synapse of neurons. In the chemical synapse, CD111 interacts with PVRL3 and both proteins can be found in neuronal tissue already in early stages of brain development as well as in aging brains. CD111 also functions as an entry receptor for herpes simplex virus and pseudorabies virus.

Specifications

General

Clone	R1.302
Clonality	monoclonal
Isotype	mouse IgG1κ
Isotype control	Isotype Control Antibody, mouse IgG1
Host	mouse
Type of antibody	Primary antibodies
Species reactivity	human
Antigen	CD111
Molecular mass of antigen [kDa]	54
Distribution of antigen	other
Entrez Gene ID	5818
RRID	AB_2654535, AB_2654537, AB_2654536, AB_2654540, AB_2654539, AB_2654538, AB_2654534, AB_2654541, AB_2654533, AB_2654542

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