Miltenyi, 130-106-291, CD107b Antibody, anti-mouse, APC

Name: CD107b Antibody, anti-mouse, APC
Brand: Miltenyi
SKU: 130-106-291

Size:30 µg in 1 mL, Bone marrow cells from CD-1 mice were fixed, permeabilized and stained with CD107b antibodies or with the corresponding isotype control antibodies (left peak). The FcR Blocking Reagent has been used to avoid Fc receptor-mediated antibody labeling. Flow cytometry was performed with the MACSQuant® Analyzer. Cell debris were excluded from the analysis based on scatter signals.

Catalog Number: 130-106-291

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Category

Rat Isotype Controls

Pack Size30 µg

TagsMACS Antibodies Hybridomas

Description

Overview
Clone M3/84 recognizes the mouse CD107b antigen, a highly glycosylated 110 kD Single-pass type I membrane protein also known as Lysosome-associated membrane protein-2 (LAMP-2) or Mac-3 antigen. It is widely located in lysosomal membranes and the plasma membrane of macrophages and some myeloid cell lines. Under certain circumstances, e.g., after platelet activation, during granulocytic differentiation and activation, in malignant carcinoma cells, and in cytotoxic T lymphocytes, it is also found at the cell surface. CD107b has been described as a receptor for the selective import and degradation of cytosolic proteins in the lysosome, or chaperone-mediated autophagy.

Specifications

General

Clone	M3/84
Clonality	monoclonal
Isotype	rat IgG1κ
Isotype control	Isotype Control Antibody, rat IgG1
Host	rat
Type of antibody	Primary antibodies
Species reactivity	mouse
Antigen	CD107b
Molecular mass of antigen [kDa]	43
Distribution of antigen	macrophages
Entrez Gene ID	16784
RRID	AB_2654523, AB_2654522, AB_2654524, AB_2654520, AB_2654517, AB_2654518, AB_2654519, AB_2654516, AB_2654515, AB_2654521

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