Miltenyi, 130-108-354, CD105 Antibody, anti-mouse, PE-Vio® 770

Name: CD105 Antibody, anti-mouse, PE-Vio® 770
Brand: Miltenyi
SKU: 130-108-354

Size:30 µg in 1 mL, Bone marrow cells from BALB/c mice were stained with CD105 antibodies or with the corresponding isotype control (left image) as well as with Anti- Sca-1 antibodies. Flow cytometry was performed using the MACSQuant® Analyzer. Cell debris and dead cells were excluded from the analysis based on scatter signals and propidium iodide fluorescence.

Catalog Number: 130-108-354

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Category

Rat Isotype Controls

Pack Size30 µg

TagsMACS Antibodies Hybridomas

Description

Overview
The CD105 antibody (clone MJ7/18) recognizes the CD105 antigen, also known as endoglin. CD105 is a proliferation-associated and hypoxia-inducible protein, abundantly expressed in angiogenic endothelial cells. In mouse bone marrow, CD105 is also expressed on a population of Sca-1+ hematopoietic stem cells (HSCs). This population has a long-term repopulating (LTR) capacity and is therefore termed LTR-HSCs1,2. Furthermore, on liver sinusoidal endothelial cells (LSEC), CD105 is co-expressed with CD146 (LSEC).

Specifications

General

Clone	MJ7/18
Clonality	monoclonal
Isotype	rat IgG2aκ
Isotype control	Isotype Control Antibody, rat IgG2a
Host	rat
Type of antibody	Primary antibodies
Species reactivity	mouse
Antigen	CD105
Molecular mass of antigen [kDa]	67
Distribution of antigen	endothelial cells, monocytes, stem cells, mesenchymal stem cells, leukemia cells, bone marrow
Entrez Gene ID	13805
RRID	AB_2660100, AB_2660094, AB_2660092, AB_2660091, AB_2660095, AB_2660093, AB_2660090, AB_2660097, AB_2660098, AB_2660099, AB_2660096, AB_1103219, AB_2660101

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