Miltenyi, 130-110-071, CD49e Antibody, anti-mouse/rat, Biotin

Name: CD49e Antibody, anti-mouse/rat, Biotin
Brand: Miltenyi
SKU: 130-110-071

Size:30 µg in 1 mL, Bone marrow cells from C57BL/6 mice were stained with CD49e antibodies as well as with CD45R (B220) antibodies. The specificity of the conjugated antibodies is confirmed by blocking the binding to ligand, using pure unconjugated antibodies (left image). The FcR Blocking Reagent has been used to avoid Fc receptor–mediated antibody labeling. Flow cytometry was performed using the MACSQuant® Analyzer. Cell debris and dead cells were excluded from the analysis based on scatter si

Catalog Number: 130-110-071

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Category

Biotin-Conjugated Secondary Antibodies

Pack Size30 µg

TagsMACS Antibodies Hybridomas

Description

Overview
Clone HMα5-1 recognizes the mouse and rat CD49e antigen, also known as integrin alpha-5, which is a protein belonging to the integrin alpha chain family. Integrins are cell-surface receptors, expressed as heterodimers essential in various processes mediating intercellular or cellmatrix interaction. Integrin alpha-5 is composed of a heavy and a light chain linked by a disulfide bond. CD49e associates non-covalently with the integrin beta-1 (CD29) forming the very late activation antigen-5 (VLA5) complex. It is expressed on different cell types including thymocytes, mast cells, activated T cells, and splenic B cells.

Specifications

General

Clone	HMα5-1
Clonality	monoclonal
Isotype	hamster IgG
Host	hamster
Type of antibody	Primary antibodies
Species reactivity	mouse, rat
Antigen	CD49e
Molecular mass of antigen [kDa]	110
Distribution of antigen	T cells, B cells, mast cells, thymocytes
Entrez Gene ID	16402
RRID	AB_2658546, AB_2658542, AB_2658545, AB_2658547, AB_2658551, AB_2658543, AB_2658548, AB_2658544, AB_2658549, AB_2658550

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