Miltenyi, 130-110-088, CD167a (DDR1) Antibody, anti-human, Biotin

Name: CD167a (DDR1) Antibody, anti-human, Biotin
Brand: Miltenyi
SKU: 130-110-088

Size:100 tests in 1 mL, MCF-7 cells were stained with CD167a (DDR1) antibodies. The specificity of the conjugated antibodies is confirmed by blocking the binding to ligand, using pure unconjugated antibodies (left peak). Flow cytometry was performed using the MACSQuant® Analyzer. Cell debris and dead cells were excluded from the analysis based on scatter signals and propidium iodide fluorescence.

Catalog Number: 130-110-088

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Category

Biotin-Conjugated Secondary Antibodies

Pack Size100 tests

TagsMACS Antibodies Hybridomas

Description

Overview
Clone 51D6 recognizes the human CD167a antigen, a single-pass type I membrane protein, which is also known as discoidin domain receptor (DDR1), mammary carcinoma kinase 10 (MCK-10), or tyrosine kinase receptor E (trkE). CD167a is a tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival, and cell proliferation. It promotes smooth muscle cell migration, and thereby contributes to arterial wound healing. CD167a also plays a role in tumor cell invasion. Three isoforms of CD167a have been reported. CD167a is expressed on epithelial cells, keratinocytes, leukocytes, monocytes, and has been reported to be overexpressed in some breast carcinomas.

Specifications

General

Clone	51D6
Clonality	monoclonal
Isotype	mouse IgG3κ
Host	mouse
Type of antibody	Primary antibodies
Species reactivity	human
Antigen	CD167a (DDR1)
Molecular mass of antigen [kDa]	99
Distribution of antigen	epithelial cells, monocytes, keratinocytes, breast
Entrez Gene ID	780
RRID	AB_2655535, AB_2655534

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