Miltenyi, 130-110-920, Human FGF-9, research grade

Biological activity

Background information
Fibroblast growth factor 9 (FGF-9), also known as heparin-binding growth factor 9 (HBGF-9), is a member of the FGF family. FGF-9 binds several FGF receptors, FGFR 1c, 2c, 3b, 3c and 4, and, like all FGF members, plays a crucial role as a cell mitogen and regulator of cell differentiation. In the nervous system, FGF-9 is secreted by neurons and induces survival signals for glial cells and astrocytes. During embryogenesis, FGF-9 is a key factor in gonad development and determination of sexual phenotype, as well as skeletal development. FGF-9 is also expressed in prostate and brain cancer.

Quality description
Research-grade cytokines are suitable for a wide variety of cell culture applications. They are sterile-filtered prior to lyophilization. Generally, endotoxin levels are <0.1 ng/μg (<1 EU/μg), and purities are >95%. The biological activity is tested in appropriate bioassays.

Overview
FGF-9 stands for fibroblast growth factor 9. Human FGF-9 is a recombinant protein optimized for use in cell culture, differentiation studies, and functional assays.