Miltenyi, 130-113-419, CD271 (LNGFR) Antibody, anti-human, Biotin

Name: CD271 (LNGFR) Antibody, anti-human, Biotin
Brand: Miltenyi
SKU: 130-113-419

Size:100 tests in 200 µL, Jurkat cells were transfected with the human LNGFR gene. Cells were stained with CD271 (LNGFR) antibodies or with the corresponding isotype control (left peak) and analyzed by flow cytometry using the MACSQuant® Analyzer. The Tandem Signal Enhancer has been used to increase binding specificity of tandem-dye–conjugated antibodies. Cell debris and dead cells were excluded from the analysis based on scatter signals and propidium iodide fluorescence or 4', 6-diamidino-2-phe

Catalog Number: 130-113-419

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Category

Mesenchymal Stem Cells

Pack Size100 tests

TagsMACS Antibodies Hybridomas

Description

Overview
Clone ME20.4-1.H4 recognizes the CD271 antigen, also known as low-affinity nerve growth factor receptor (LNGFR) or neurotrophin receptor (p75 NTR). CD271 belongs to the low-affinity neurotrophin receptors and the tumor necrosis factor receptor superfamily. Initially the human CD271 (LNGFR) was described to be expressed on cells of the central and peripheral nervous system, and was suggested to be involved in the development, survival, and differentiation of cells.1
CD271 (LNGFR) is expressed on
- Mesenchymal stem/stromal cells (MSCs)2,3,4
- Follicular dendritic cells5
- Mesenchymal cells involved in mesenchymal-epithelial interactions6
- Autonomic and sensory Neurons7
- Oligodendrocytes8
- Astrocytes9
- Schwann cells10,11
- Neural crest stem cells12

Specifications

General

Clone	ME20.4-1.H4
Clonality	monoclonal
Isotype	mouse IgG1κ
Isotype control	Isotype Control Antibody, mouse IgG1
Host	mouse
Type of antibody	Primary antibodies
Species reactivity	human, non-human primate, other
Cross-reactivity	monkey, goat, dog, pig, sheep
Antigen	CD271 (LNGFR)
Molecular mass of antigen [kDa]	43
Distribution of antigen	B cells, stem cells, dendritic cells, monocytes, neurons, cancer stem cells, mesenchymal stem cells, bone marrow
Entrez Gene ID	4804
RRID	AB_2733631, AB_2733630, AB_2733936, AB_2733220, AB_2733512, AB_2733362, AB_2733363, AB_2733219, AB_2733794, AB_2733513, AB_2734063, AB_2734064, AB_2733937, AB_2733795

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