Miltenyi, 130-115-182, CD105 Antibody, anti-human, FITC, REAlease®

Name: CD105 Antibody, anti-human, FITC, REAlease®
Brand: Miltenyi
SKU: 130-115-182

Size:100 tests in 200 µL, Human Umbilical Vein Endothelial Cells (HUVEC) were stained with REAlease CD105-FITC (B) or with the corresponding REAL Control (A). REAlease CD105-FITC was released using the REAlease Release Reagent (C). To show epitope accessibility after REAlease Complex release, the cells were washed with the REAlease Stop Reagent and restained with REAlease CD105-FITC (D). Cells were and analyzed by flow cytometry using the MACSQuant® Analyzer. Cell debris and dead cells were excl

Catalog Number: 130-115-182

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Category

Recombinant Antibodies

Pack Size100 tests

TagsMACS Antibodies Releasable antibodies

Description

Overview
Clone REAL218 is an antibody fragment derived from the full CD105 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAlease Complex to bind markers with high avidity.
Clone REAL218 recognizes the CD105 antigen, also known as endoglin, which serves as a receptor for the growth and differentiation factors TGF-β1 and TGF-β3. An epitope of CD105 is recognized by the SH-2 antibody, which was raised against human mesenchymal stromal cells (MSC) that show mesodermal differentiation capacity. Therefore, it can be used for studies on mesengenesis. CD105 is also expressed on mature endothelial cells and on some leukemic cells of B lymphoid and myeloid origin.
The REAlease Kits consist of the respective fluorochrome-conjugated REAlease Complexes and the REAlease Support Kit for removal of the REAlease Complexes and optional relabeling with different fluorochrome-conjugated REAlease Complexes.

Specifications

General

Clone	REAL218
Clonality	monoclonal
Isotype control	Control Antibody
Host	cell line
Type of antibody	Releasable antibodies, Primary antibodies, Recombinant antibodies
Species reactivity	human
Antigen	CD105
Distribution of antigen	endothelial cells, B cells, myeloid cells
RRID	AB_2819671, AB_2751254, AB_2751248, AB_2819672, AB_2783903

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