Miltenyi, 130-121-278, CD90.2 MicroBeads, mouse

Background information
The mouse CD90.2 alloantigen, also known as Thy1.2, is a pan T cell marker for the most common inbred mouse strains. These strains include BALB/c, DBA, CBA/J, C3H, C57BL/6, NZB/-, S3L and others. CD90.2 is expressed on thymocytes, peripheral T cells, on some intraepithelial T cells, and at lower levels on early hematopoietic stem cells in bone marrow.
The mouse CD90.2 antibody does not cross-react with CD90.1 (Thy1.1).

Downstream applications
- T cells isolated with CD90.2 MicroBeads were used to analyze cytokine expression in a mouse model of lung fibrosis or after adoptive transfer of T cells from wild type and knock-out mice into immunodeficient mice.
- Furthermore, CD90.2 MicroBeads were used for the isolation of tumor-infiltrating T cells to evaluate their immunotherapeutic potential or functional properties.

Columns
For positive selection: MS, LS, or autoMACS® Columns. For depletion: LD or autoMACS Columns.

Overview
CD90.2 MicroBeads were developed for positive selection or depletion of mouse T cells from single-cell suspensions of lymphoid and non-lymphoid tissues or from peripheral blood.