Miltenyi, 130-123-291, CD43 Antibody, anti-human, APC-Vio® 770

Name: CD43 Antibody, anti-human, APC-Vio® 770
Brand: Miltenyi
SKU: 130-123-291

Size:100 tests in 200 µL, Human peripheral blood mononuclear cells (PBMCs) were stained with CD43 antibodie as well as with CD19 antibodies and analyzed by flow cytometry using the MACSQuant® Analyzer. Cell debris and dead cells were excluded from the analysis based on scatter signals and propidium iodide fluorescence or 4', 6-diamidino-2-phenylindole (DAPI) fluorescence, as in the case of tandems.

Catalog Number: 130-123-291

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Category

Mesenchymal Stem Cells

Pack Size100 tests

TagsMACS Antibodies Hybridomas

Description

Overview
Human CD43 (leukosialin) is a cell surface sialoglycoprotein that is involved in cell adhesion, differentiation and activation. The CD43 antigen is expressed on most leukocytes, i.e., T cells, NK cells, granulocytes, monocytes, and macrophages, on hematopoietic stem cells, and on platelets, but not on erythrocytes. Among B cells, CD43 is expressed on activated B cells and plasma cells but not on resting B cells, e.g., naive B cells. In bone marrow, CD43 is found on pro-B cells but is down-regulated during transition to the pre-B cell stage. CD43 is expressed on different myeloid and lymphoid tumors, including some B cell malignancies.

Specifications

General

Clone	DF-T1
Clonality	monoclonal
Isotype	mouse IgG1κ
Isotype control	Isotype Control Antibody, mouse IgG1
Host	mouse
Type of antibody	Primary antibodies
Species reactivity	human, non-human primate
Cross-reactivity	rhesus monkey (Macaca mulatta), olive baboon (Papio anubis)
Antigen	CD43
Molecular mass of antigen [kDa]	38
Distribution of antigen	B cells, granulocytes, macrophages, megakaryocytes, T cells, monocytes, NK cells, platelets, red blood cells, lymphocytes, stem cells, basophils, mesenchymal stem cells, neutrophils, plasma cells, thymocytes, bone marrow
Entrez Gene ID	6693
RRID	AB_2922371, AB_2658128, AB_2658131, AB_2658125, AB_2819468, AB_2922370, AB_2876908, AB_2876909, AB_2658139, AB_2658138, AB_2658137, AB_2819480, AB_2658136, AB_2922079, AB_2922046

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