Miltenyi, 130-124-361, CD107a (LAMP-1) Antibody, anti-human, FITC, REAdye_lease™

Name: CD107a (LAMP-1) Antibody, anti-human, FITC, REAdye_lease™
Brand: Miltenyi
SKU: 130-124-361

Size:200 µL, Immunofluorescence analysis of a human tonsil cryosection fixed with ice-cold acetone. The section was stained using CD107a (LAMP-1) Antibody, anti-human, FITC (green) for 10 min at room temperature (A). CD107a (LAMP-1) Antibody, anti-human, FITC staining was released using the REAlease Release Reagent (B). Nuclei were visualized with Hoechst™ (blue). Scale bar: 30 µm.

Catalog Number: 130-124-361

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Category

Recombinant Antibodies

Pack Size200 µL

TagsMACS Antibodies Releasable fluorochromes

Description

Overview
Clone REAL565 is an antibody fragment derived from the full CD107a antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity.
Clone REAL565 recognizes the CD107a antigen, also known as lysosome-associated membrane protein 1 (LAMP-1), a 110–140 kDa type I membrane glycoprotein. It is a widely expressed intracellular protein, located in the lysosomal/endosomal membrane. CD107a transiently located on the plasma membrane can be used as a marker for CD8+ T cell degranulation following stimulation. It is also expressed to a lower extent on activated NK cells.
For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675).

Specifications

General

Clone	REAL565
Clonality	monoclonal
Isotype control	Control Antibody
Host	cell line
Type of antibody	Releasable fluorochromes, Primary antibodies, Recombinant antibodies
Species reactivity	human
Antigen	CD107a (LAMP-1)
Distribution of antigen	dendritic cells, endothelial cells, epithelial cells, granulocytes, macrophages, platelets, T cells, neutrophils, tonsil, spleen
RRID	AB_2857700, AB_2857701

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