Miltenyi, 130-126-171, CD200 Antibody, anti-human, APC

Name: CD200 Antibody, anti-human, APC
Brand: Miltenyi
SKU: 130-126-171

Size:100 tests in 200 µL, Human peripheral blood mononuclear cells (PBMCs) were stained with CD200 antibodies as well as with CD19 antibodies and analyzed by flow cytometry using the MACSQuant® Analyzer. Cell debris and dead cells were excluded from the analysis based on scatter signals and propidium iodide fluorescence.

Catalog Number: 130-126-171

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Category

Mesenchymal Stem Cells

Pack Size100 tests

TagsMACS Antibodies Hybridomas

Description

Overview
Clone OX-104 reacts with the human CD200 antigen, also known as MRC, MOX1/2, and OX-2, a type-1 membrane glycoprotein, which contains two immunoglobulin domains. Studies of the related gene in mouse and rat suggest that CD200 may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. CD200 may serve as a cancer stem cell marker as co-expression with other reported stem cell markers was found on prostate, breast, brain, and colon cancers. In addition, CD200 expression was shown to be a prognostic factor in AML and multiple myeloma.

Specifications

General

Clone	OX-104
Clonality	monoclonal
Isotype	mouse IgG1κ
Isotype control	Isotype Control Antibody, mouse IgG1
Host	mouse
Type of antibody	Primary antibodies
Species reactivity	human
Antigen	CD200
Molecular mass of antigen [kDa]	28
Distribution of antigen	B cells, dendritic cells, endothelial cells, T cells, neurons, mesenchymal stem cells, ES and iPS cells, smooth muscle
Entrez Gene ID	4345
RRID	AB_2889497, AB_2857676, AB_2656111, AB_2656107, AB_2656108, AB_2889496, AB_2857688

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