Miltenyi, 130-126-432, Caldesmon Antibody, anti-human, APC, REAdye_lease™

Name: Caldesmon Antibody, anti-human, APC, REAdye_lease™
Brand: Miltenyi
SKU: 130-126-432

Size:200 µL, Immunofluorescence analysis of a human kidney cryosection fixed with 4% PFA. The section was stained using Caldesmon Antibody, anti-human, Vio® B515 (green) for 10 min at room temperature. Nuclei were visualized with Hoechst™ (blue). Scale bar: 30 µm.

Catalog Number: 130-126-432

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Category

Recombinant Antibodies

Pack Size200 µL

TagsMACS Antibodies Releasable fluorochromes

Description

Overview
Clone REAL657 is an antibody fragment derived from the full Caldesmon antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity.
Clone REAL657 recognizes the human protein Caldesmon, which is a calmodulin binding protein that is involved in the regulation of actomyosin interactions in smooth muscle and nonmuscle cells by inhibiting the ATPase activity of myosin in smooth muscle. It is also implicated in cellular mitosis and receptor capping and plays a role in Schwann cell migration during peripheral nerve regeneration.
Clone REAL657 recognizes the high molecular mass variant of caldesmon (h-caldesmon) and does not react with the non-muscle variant.
For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675).

Specifications

General

Clone	REAL657
Clonality	monoclonal
Isotype control	Control Antibody
Host	cell line
Type of antibody	Releasable fluorochromes, Primary antibodies, Recombinant antibodies
Species reactivity	human
Antigen	Caldesmon
Distribution of antigen	smooth muscle
RRID	AB_2904647

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