Miltenyi, 130-126-572, ACPP Antibody, anti-human, FITC, REAdye_lease™

Name: ACPP Antibody, anti-human, FITC, REAdye_lease™
Brand: Miltenyi
SKU: 130-126-572

Size:200 µL, Immunofluorescence analysis of a formalin-fixed, paraffin embedded (FFPE) human prostate. Before staining, antigens were retrieved using heat-induced epitope retrieval (HIER) at pH 9. The section was stained using ACPP Antibody, anti-human, FITC (green) for 10 min at room temperature (A). ACPP Antibody, anti-human, FITC staining was released using the REAlease Release Reagent (B). Nuclei were visualized with Hoechst™ (blue). Scale bar: 30 µm.

Catalog Number: 130-126-572

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Category

Recombinant Antibodies

Pack Size200 µL

TagsMACS Antibodies Releasable fluorochromes

Description

Overview
Clone REAL717 is an antibody fragment derived from the full ACPP antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity.
Clone REAL717 recognizes the human ACPP (acid phosphatase, prostate), also known as PAP (prostatic acid phosphatase. ACPP is a non-specific tyrosine phosphatase that dephosphorylates a diverse number of substrates under acidic conditions. ACPP has lipid phosphatase activity and inactivates lysophosphatidic acid in seminal plasma. Isoform 2 of ACPP acts as a tumor suppressor of prostate cancer through dephosphorylation of ERBB2 and deactivation of MAPK-mediated signaling. It also generates adenosine from AMP which acts as a pain suppressor.
For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675).

Specifications

General

Clone	REAL717
Clonality	monoclonal
Isotype control	Control Antibody
Host	cell line
Type of antibody	Releasable fluorochromes, Primary antibodies, Recombinant antibodies
Species reactivity	human
Antigen	ACPP
Distribution of antigen	prostate cancer cells, prostate
RRID	AB_2904624, AB_2904625

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