Miltenyi, 130-127-354, ACTC1 Antibody, anti-human, APC, REAdye_lease™

Name: ACTC1 Antibody, anti-human, APC, REAdye_lease™
Brand: Miltenyi
SKU: 130-127-354

Size:200 µL, Immunofluorescence analysis of a formalin-fixed, paraffin embedded (FFPE) human heart. Before staining, antigens were retrieved using heat-induced epitope retrieval (HIER) at pH 9. The section was stained using ACTC1 Antibody, anti-human, PE (green) for 10 min at room temperature (A). ACTC1 Antibody, anti-human, PE staining was released using the REAlease Release Reagent (B). Nuclei were visualized with Hoechst™ (blue). Scale bar: 30 µm.

Catalog Number: 130-127-354

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Category

Recombinant Antibodies

Pack Size200 µL

TagsMACS Antibodies Releasable fluorochromes

Description

Overview
Clone REAL970 is an antibody fragment derived from the full ACTC1 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity.
Clone REAL970 recognizes ACTC1, which is also known as cardiac muscle alpha actin or Alpha-cardiac actin. It is an important protein of the thin filament in cardiac sarcomeres, which play a crucial role in muscle contraction and support the pump function of the heart. It belongs to the actin family, highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in eukaryotic cells. Mutations in ACTC1 lead to dilated cardiomyopathy. ACTC1 is considered as a prognostic marker for glioma and for liver metastasis.
For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675).

Specifications

General

Clone	REAL970
Clonality	monoclonal
Isotype control	Control Antibody
Host	cell line
Type of antibody	Releasable fluorochromes, Primary antibodies, Recombinant antibodies
Species reactivity	human
Antigen	ACTC1
Distribution of antigen	cardiac cells, muscle
RRID	AB_2904629, AB_2904627, AB_2904628

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