Miltenyi, 130-127-445, Recombinant SARS-CoV-2 RBD (insect cells)-Biotin

Name: Recombinant SARS-CoV-2 RBD (insect cells)-Biotin
Brand: Miltenyi
SKU: 130-127-445

Size:10 µg

Catalog Number: 130-127-445

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Category

Insect Cell Expression Systems

Pack Size10 µg

TagsMACS Cell Culture and Stimulation Stimulation reagents Antigens and peptide pools

Description

Overview
The receptor binding domain (RBD) is located C-terminally within the S1 subunits of the spike (S) protein. The S protein forms a homotrimeric structure on the surface of the SARS-CoV-2 virus and binds to the angiotensin-converting enzyme 2 (ACE2) receptor of target cells. Recent studies have shown that the predominant activated form displays one RBD rotated upwards into an ACE2-accessible state and it is known that binding of RBD to ACE2 is a major contributor for interaction of the S protein with its target receptor. The SARS-CoV-2 RBD (insect cells) protein covers amino acids R319 to S591 of the spike protein and contains a His-tag and an AviTag™. Recombinant SARS-CoV-2 RBD (insect cells)-Biotin is specifically biotinylated at a single site, preserving full functionality of the RBD.

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