Miltenyi, 130-130-617, 53BP1 Antibody, anti-human, PE, REAdye_lease™

Name: 53BP1 Antibody, anti-human, PE, REAdye_lease™
Brand: Miltenyi
SKU: 130-130-617

Size:200 µL, Immunofluorescence analysis of a human testis cryosection fixed with 4% PFA. The section was stained using 53BP1 Antibody, anti-human, Vio® B515 (green) for 10 min at room temperature. Nuclei were visualized with Hoechst™ (blue). Scale bar: 30 µm.

Catalog Number: 130-130-617

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Category

Recombinant Antibodies

Pack Size200 µL

TagsMACS Antibodies Releasable fluorochromes

Description

Overview
Clone REAL1211 is an antibody fragment derived from the full 53BP1 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity.
Clone REAL1211 recognizes the human 53BP1 (tumor protein p53 binding protein 1), a Double-strand break (DSB) repair protein involved in response to DNA damage, telomere dynamics and class-switch recombination (CSR) during antibody genesis. It promotes NHEJ of dysfunctional telomeres via interaction with PAXIP1.
For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675).

Specifications

General

Clone	REAL1211
Clonality	monoclonal
Isotype control	Control Antibody
Host	cell line
Type of antibody	Releasable fluorochromes, Primary antibodies, Recombinant antibodies
Species reactivity	human
Antigen	53BP1
Distribution of antigen	ubiquitous
RRID	AB_2928169

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