Miltenyi, 130-131-050, Calsequestrin 2 Antibody, anti-human, Vio® B515, REAdye_lease™

Name: Calsequestrin 2 Antibody, anti-human, Vio® B515, REAdye_lease™
Brand: Miltenyi
SKU: 130-131-050

Size:200 µL, Immunofluorescence analysis of a formalin-fixed, paraffin embedded (FFPE) human heart. Before staining, antigens were retrieved using heat-induced epitope retrieval (HIER) at pH 9. The section was stained using Calsequestrin 2 Antibody, anti-human, FITC (green) for 10 min at room temperature (A). Calsequestrin 2 Antibody, anti-human, FITC staining was released using the REAlease Release Reagent (B). Nuclei were visualized with Hoechst™ (blue). Scale bar: 30 µm.

Catalog Number: 130-131-050

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Category

Recombinant Antibodies

Pack Size200 µL

TagsMACS Antibodies Releasable fluorochromes

Description

Overview
Clone REAL1060 is an antibody fragment derived from the full Calsequestrin 2 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity.
Clone REAL1060 recognizes Calsequestrin 2, also known as CASQ2. Calsequestrin 2 is a major Ca2+-storage/buffer protein present in the sarcoplasmic reticulum of cardiac (CASQ2) muscles. It plays a role in excitation-contraction coupling in the heart and in regulating the rate of heart beats. Calsequestrin 2 is identified as a breast cancer-related gene in tumor-microenvironment interactions during tumor growth and metastasis.
For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675).

Specifications

General

Clone	REAL1060
Clonality	monoclonal
Isotype control	Control Antibody
Host	cell line
Type of antibody	Releasable fluorochromes, Primary antibodies, Recombinant antibodies
Species reactivity	human
Antigen	Calsequestrin 2
Distribution of antigen	cardiac cells
RRID	AB_2928190, AB_2928191

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