Miltenyi, 130-131-852, Carboxypeptidase A1 Antibody, anti-human, PE, REAdye_lease™

Name: Carboxypeptidase A1 Antibody, anti-human, PE, REAdye_lease™
Brand: Miltenyi
SKU: 130-131-852

Size:200 µL, Immunofluorescence analysis of a formalin-fixed, paraffin embedded (FFPE) human pancreas. Before staining, antigens were retrieved using heat-induced epitope retrieval (HIER) at pH 9. The section was stained using Carboxypeptidase A1 Antibody, anti-human, PE (green) for 10 min at room temperature. Nuclei were visualized with Hoechst™ (blue). Scale bar: 30 µm.

Catalog Number: 130-131-852

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Category

Recombinant Antibodies

Pack Size200 µL

TagsMACS Antibodies Releasable fluorochromes

Description

Overview
Clone REAL1385 is an antibody fragment derived from the full Carboxypeptidase A1 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity.
Clone REAL1385 recognizes the zinc metalloprotease Carboxypeptidase A1, encoded by the CPA1 gene and belongs to the peptidase M14 family. It is a monomeric pancreatic exopeptidase, that catalyzes the release of a C-terminal amino acid, the conversion of leukotriene C4 to leukotriene F4 and is involved in zymogen inhibition. CPA1 is associated with pancreatic cancer susceptibility and implicate ER stress in pancreatic acinar cells in pancreatic cancer development.
For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675).

Specifications

General

Clone	REAL1385
Clonality	monoclonal
Isotype control	Control Antibody
Host	cell line
Type of antibody	Releasable fluorochromes, Primary antibodies, Recombinant antibodies
Species reactivity	human
Antigen	Carboxypeptidase A1
Distribution of antigen	pancreatic carcinoma cells, pancreas
RRID	AB_2928194

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