Miltenyi, 130-132-858, BCA-225 (BRST1) Antibody, anti-human, Vio® B515, REAdye_lease™

Name: BCA-225 (BRST1) Antibody, anti-human, Vio® B515, REAdye_lease™
Brand: Miltenyi
SKU: 130-132-858

Size:200 µL, Immunofluorescence analysis of a formalin-fixed, paraffin embedded (FFPE) human breast cancer. Before staining, antigens were retrieved using heat-induced epitope retrieval (HIER) at pH 9. The section was stained using BCA-225 (BRST1) Antibody, anti-human, Vio® B515 (green) for 10 min at room temperature. Nuclei were visualized with Hoechst™ (blue). Scale bar: 30 µm.

Catalog Number: 130-132-858

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Category

Recombinant Antibodies

Pack Size200 µL

TagsMACS Antibodies Releasable fluorochromes

Description

Overview
Clone REAL1414 is an antibody fragment derived from the full BCA-225 (BRST1) antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity.
Clone REAL1414 recognizes BCA-225 (BRST1), a carcinoma-associated glycoprotein and member of a family that includes at least two type I membrane proteins. It is expressed on most normal epithelial cells, breast, kidney, ovary and lung carcinomas and other adenocarcinomas. It functions as a homotypic calcium-independent cell adhesion molecule. Clone REAL1414 specifically recognizes breast carcinoma cells and is reported as a highly sensitive marker of breast carcinomas, both in the primary tumor and in its metastases.
For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675).

Specifications

General

Clone	REAL1414
Clonality	monoclonal
Isotype control	Control Antibody
Host	cell line
Type of antibody	Releasable fluorochromes, Primary antibodies, Recombinant antibodies
Species reactivity	human
Antigen	BCA-225 (BRST1)
Distribution of antigen	epithelial cells, tumor cells, breast cancer cells, lung cancer cells, other

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