Miltenyi, 130-135-425, Caveolin-1 Antibody, anti-human, Vio® B515, REAdye_lease™

Name: Caveolin-1 Antibody, anti-human, Vio® B515, REAdye_lease™
Brand: Miltenyi
SKU: 130-135-425

Size:200 µL, Immunofluorescence analysis of a formalin-fixed, paraffin embedded (FFPE) human lung. Before staining, antigens were retrieved using heat-induced epitope retrieval (HIER) at pH 9. The section was stained using Caveolin-1 Antibody, anti-human, PE (green) for 10 min at room temperature (A). Caveolin-1 Antibody, anti-human, PE staining was released using the REAlease Release Reagent (B). Nuclei were visualized with Hoechst™ (blue). Scale bar: 30 µm.

Catalog Number: 130-135-425

Pricing

Send an RFQ.

View RFQ List

Category

Recombinant Antibodies

Pack Size200 µL

TagsMACS Antibodies Releasable fluorochromes

Description

Overview
Clone REAL686 is an antibody fragment derived from the full Caveolin-1 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity.
Clone REAL686 recognizes the Caveolin-1 protein, a main component of the caveolae plasma membranes found in most cell types. It links integrin subunits to the tyrosine kinase FYN and promots cell cycle progression. The coding CAV1 is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. Caveolin 1 has been shown to interact with a range of molecules via caveolin-binding motifs (CBM) through a caveolin-scaffolding domain (CSD) within caveolin-1 molecule. High Caveolin-1 levels were correlated with tumor progression, invasion and metastasis.
For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675).

Specifications

General

Clone	REAL686
Clonality	monoclonal
Isotype control	Control Antibody
Host	cell line
Type of antibody	Releasable fluorochromes, Primary antibodies, Recombinant antibodies
Species reactivity	human
Antigen	Caveolin-1
Distribution of antigen	tumor cells
RRID	AB_2904649

Ordering

Notice

Unless otherwise stated, the minimum order amount is USD 1,000.
For orders below USD 1,000, an additional handling fee may apply, or we may arrange local delivery / local handover where available.
All quotations are subject to final confirmation, including product availability, lead time, batch information, shipping cost, and applicable export or handling requirements.
For quotation requests, please send an RFQ from website or contact:

[email protected]

Please send inquiries directly to us in the “To” field. Emails sent via BCC, mass mailing, or with unrelated recipients may be automatically filtered and will not be processed.