Miltenyi, 130-138-917, Human BMP-7, research grade

Name: Human BMP-7, research grade
Brand: Miltenyi
SKU: 130-138-917

Size:10 µg

Catalog Number: 130-138-917

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Category

Alkaline Phosphatase-Conjugated Secondary Antibodies

Pack Size10 µg

TagsMACS Cell Culture and Stimulation Cytokines and growth factors Premium and research grade

Description

Biological activity

Background information
Bone morphogenetic protein 7 (BMP-7) is a member of the BMP family and the transforming growth factor beta (TGF-β) superfamily. BMPs regulate the development and remodeling of bone and cartilage by acting on cell proliferation, differentiation, and apoptosis of mesenchymal cells. The mature form of BMP-7 is generated by cleavage of the signal peptide and propeptide and homo-dimerization. BMP-7 is involved in osteoblast differentiation, but also in the regulation of tissue and organ development during embryogenesis in various species, and is expressed in many organs. BMP-7 is extensively studied for clinical applications and recombinant BMP-7 is used in bone regeneration, bone grafting, and dental reconstruction. Recombinant human BMP-7 corresponds to the mature form of BMP-7.

Overview
BMP-7 stands for bone morphogenetic protein 7. Human BMP-7 is a recombinant protein optimized for use in cell culture, differentiation studies, and functional assays.

Specifications

General

Determination method	Alkaline phosphatase activity assay using ATDC-5 cells
Research grade	≥ 3.6×103 U/mg

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