Miltenyi, 130-138-940, Human IL-11, research grade

Name: Human IL-11, research grade
Brand: Miltenyi
SKU: 130-138-940

Size:100 µg

Catalog Number: 130-138-940

Pricing

Send an RFQ.

View RFQ List

Category

Human Primary Cells

Pack Size100 µg

TagsMACS Cell Culture and Stimulation Cytokines and growth factors Premium and research grade

Description

Biological activity

Background information
Interleukin 11 (IL-11) is a multifunctional cytokine belonging to the IL-6 family. It is found in various organs and tissues and is secreted by mesenchymal cells including fibroblasts, stromal cells, osteoclasts and epithelial cells. The IL-11 receptor is a heterodimeric protein expressed by different hematopoietic lineages such as megakaryocytes, erythroid and myeloid progenitors. In combination with other cytokines (IL-4, IL-3 and SCF), IL-11 regulates several hematopoietic processes, including megakaryocyte maturation.
IL-11 activates certain B and T cells and plays a role in primary and secondary immune responses as a modulator of autoinflammation in favor of Th2 polarization and allergic reactions. IL-11 is also involved in the regulation of osteoclast differentiation and blastocyst implantation. IL-11 is being investigated for the treatment of osteoporosis, thrombocytopenia and inflammatory conditions.

Overview
Human IL-11 is a recombinant protein optimized for use in cell culture, differentiation studies, and functional assays.

Specifications

General

Determination method	Ability to induce alkaline phosphatase production in a HEK293 reporter cell line
Research grade	≥ 1×107 U/mg

Ordering

Notice

Unless otherwise stated, the minimum order amount is USD 1,000.
For orders below USD 1,000, an additional handling fee may apply, or we may arrange local delivery / local handover where available.
All quotations are subject to final confirmation, including product availability, lead time, batch information, shipping cost, and applicable export or handling requirements.
For quotation requests, please send an RFQ from website or contact:

[email protected]

Please send inquiries directly to us in the “To” field. Emails sent via BCC, mass mailing, or with unrelated recipients may be automatically filtered and will not be processed.