Miltenyi, 130-139-858, Anti-TCRVδ1 MicroBeads, human

Background information
Vδ1 T cells are a distinct subset of γδ T lymphocytes, primarily enriched in epithelial tissues such as the gut and skin but are also found in peripheral blood. Unlike conventional αβ T cells, Vδ1 T cells recognize antigens in an MHC-independent manner, allowing fast responses to stressed or infected cells. Functionally, Vδ1 T cells exhibit both cytotoxic and cytokine-secreting capacities, producing IFN-γ and TNF-α.

Downstream applications
Isolated Vδ1 T cells can be utilized in functional killing assays, tumor co-culture models, Vδ1-based adoptive cell therapy development and CAR-Vδ1 engineering and expansion studies.

Columns
For positive selection: MS, LS, XS, or autoMACS® Columns. For depletion: LD, D, or autoMACS Columns.

Overview
Anti-TCRVδ1 MicroBeads were developed for the rapid positive selection of TCRVδ1 cells, a subset of γδ T cells, from PBMCs.