Miltenyi, 170-076-164, MACS® GMP PepTivator® Melanoma Select

Background information
The MACS® GMP PepTivator Melanoma Select is a peptide pool of 14 lyophilized oligopeptides, consisting of lyophilized MHC class I and class II restricted peptides derived from 5 proteins, commonly expressed by melanoma cells: GP100, MAGEA3, MAGE-C2, NY-ES01 and Tyrosinase. The peptides are restricted for the following HLA-molecules: HLA-A*01, -A*02, -A*03, -A*31, -B*35, -B*44, -C*07, -DR4, -DP4, -DQ6.

Applications
MACS® GMP PepTivator Melanoma Select can be used for a variety of applications, for example, in vitro stimulation of melanoma antigen-specific CD4+ and CD8+ T cells.
This product has not yet been tested in conjunction with the CliniMACS Cytokine Capture System (IFN-gamma).

Quality statement
MACS GMP Products are manufactured and tested under a quality management system (ISO 13485) and are in compliance with relevant GMP guidelines. They are designed following the recommendations of USP <1043> on ancillary materials.

Disclaimer
MACS GMP Products are for ex vivo cell processing only, and are not intended for human in vivo applications. For regulatory status in the USA, please contact your local representative.

Overview
The MACS® GMP PepTivator Melanoma Select is a peptide pool that consists mainly of 15-mer peptides. It has been developed for the efficient in vitro stimulation and subsequent isolation of antigen-specific CD4+ and CD8+ T cells.