Miltenyi, 170-076-308, MACS® GMP Rapamycin

Background information
MACS GMP Rapamycin is sufficient for the supplementation of 2000 mL TexMACS GMP Medium and used in expansion protocols for regulatory T cells (Treg cells). Rapamycin inhibits the expansion of conventional T cells and thereby enhances the proportion of expanded Treg cells in culture.1

Applications
The manufacturing of a large number of Treg cells for clinical research can be achieved with the use of the MACS GMP ExpAct Treg Kit, TexMACS GMP Medium supplemented with MACS GMP Rapamycin and the CliniMACS CD25 enrichment procedure.

Quality statement
MACS GMP Products are manufactured and tested under a quality management system (ISO 13485) and are in compliance with relevant GMP guidelines. They are designed following the recommendations of USP <1043> on ancillary materials.

Disclaimer
MACS GMP Products are for ex vivo cell processing only, and are not intended for human in vivo applications. For regulatory status in the USA, please contact your local representative.

Overview
The content of MACS GMP Rapamycin is sufficient to result in a 100 nM ready-to-use Treg expansion medium in combination with TexMACS™ GMP Medium (2000 mL).