Description
Background information
Features
- Weldable tubing from supplement bag to basal medium bag ensures simplified handling
- Media designed and optimized for efficient expansion of MSCs
- Lot-to-lot consistency ensured by xeno-free media composition and standardized manufacturing procedures
Bag Format
The MSC-Brew GMP Medium is now reformulated to include a single supplement in a bag, enabling a fully closed system for clinical cell manufacturing. This design enhances safety and regulatory compliance, minimizes contamination risks, and simplifies handling by allowing direct connection between supplement bag and basal medium bag through weldable tubing.
Optimized for use with the CliniMACS Prodigy ACC process, the GMP-compliant, xeno-free medium ensures reliable and scalable stem cell expansion with bioreactors at clinical settings.
Available Formats
Available in 2 sizes with vial or bag supplements to support manual and automated workflows
1. MSC-Brew GMP Medium, 500 mL (170-076-331) and MSC-Brew GMP Medium, 2000 mL (170-076-331)
- 500 mL or 2000 mL MSC-Brew GMP Basal Medium in bag
- 10 mL/ 20 mL MSC-Brew GMP Supplement in bag
Simplified handling is ensured by tube-tube connection via weldable tubing from supplement bags to basal medium bags
Seamless connection to bioreactors to scale up manufacturing of hPSCs
2. MSC-Brew GMP Medium, 500 mL (bag) (170-076-326) and MSC-Brew GMP Medium, 2000 mL (bag) (170-076-325)
- 500 mL or 2000 mL MSC-Brew GMP Basal Medium in bag
- 10 mL MSC-Brew GMP Supplement I in vial
- 10 mL MSC-Brew GMP Supplement II in vial
Applications
- For reproducible isolation and expansion of human MSCs without addition of AB-serum
- Suitable for bone marrow, adipose tissue, and umbilical cord-derived MSCs
- Optimized for both manual and automated clinical workflows including CliniMACS Prodigy ACC process and bioreactor-based manufacturing
Quality statement
MACS GMP Products are manufactured and tested under a quality management system (ISO 13485) and are in compliance with relevant GMP guidelines. They are designed following the recommendations of USP <1043> on ancillary materials.
Disclaimer
MACS GMP Products are for ex vivo cell processing only, and are not intended for human in vivo applications. For regulatory status in the USA, please contact your local representative.
Overview
MSC-Brew GMP Medium is a GMP-compliant, serum-free and xeno-free formulation designed for the reliable isolation and expansion of mesenchymal stem cells (MSCs) from human bone marrow, adipose tissue, and umbilical cord. Based on the proven research-grade StemMACS MSC Expansion Media Kit XF (130-104-182), this medium enables a seamless transition from research into clinical manufacturing while ensuring optimal cell growth.
