Proteintech, 11427-1-AP-150ul, ANKRD1 Polyclonal antibody

11427-1-AP targets ANKRD1 in WB, IF-P, IP, RIP, ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Applications
Positive WB detected in: mouse skeletal muscle tissue, rat skeletal muscle tissue
Positive IF-P detected in: mouse heart tissue
Recommended dilution
Western Blot (WB): WB : 1:500-1:3000
Immunofluorescence (IF)-P: IF-P : 1:200-1:800
Background Information
Ankyrin repeat domain-containing protein 1(ANKRD1) belongs to the conserved muscle ankyrin repeat protein(MARP) family, whose expression is induced in response to physiologic stress, injury and hypertrophy. Thus its expression mainly in activated vascular endothelial cells. ANKRD1 may regulate SMC proliferation through the CDKN1A pathway. It functions as a nuclear transcription repressor that regulate cardiac gene's expression. This is a rabbit polyclonal antibody produced by the full-length ANKRD1 of human origin