Description
18179-1-AP targets ABCD2 in WB, IP, ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Applications
Positive WB detected in: mouse adipose tissue, mouse cerebellum tissue, rat adipose tissue
Positive IP detected in: mouse adipose tissue
Recommended dilution
Western Blot (WB): WB : 1:1000-1:8000
Immunoprecipitation (IP): IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
Background Information
ABCD2 is a member of the superfamily of ATP-binding cassette (ABC) transporters, and is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. ABCD2 plays a role in regulation of VLCFAs and energy metabolism, in the degradation and biosynthesis of fatty acids by beta-oxidation (PMID:29397936, 21145416).