Description
18830-1-AP targets 1A6/DRIM in WB, IF/ICC, IP, ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Applications
Positive WB detected in: HeLa cells, HepG2 cells
Positive IP detected in: HeLa cells
Positive IF/ICC detected in: Hela cells
Recommended dilution
Western Blot (WB): WB : 1:500-1:2000
Immunoprecipitation (IP): IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
Immunofluorescence (IF)/ICC: IF/ICC : 1:20-1:200
Background Information
1A6/DRIM has been identified as UTP20, a small subunit processome component, functioning in 18S rRNA processing. 1A6/DRIM was originally identified from the malignant derivative of an immortalized gastric epithelial cell line [1] and was found to be down-regulated in metastatic breast cancer cells (PMID: 21151873, 17498821).