Proteintech, 19764-1-AP-150ul, ABCA13 Polyclonal antibody

19764-1-AP targets ABCA13 in WB, ELISA applications and shows reactivity with human samples.
Tested Applications
Positive WB detected in: HEK-293 cells, HeLa cells
Recommended dilution
Western Blot (WB): WB : 1:500-1:1000
Background Information
ABCA13 belongs to the ABC transporter superfamily. ABCA13 is a transmembrane protein with the typical structure of ABC proteins: two transmembrane domains and two nucleotide-binding domains. ABCA13 may mediate the cholesterol and gangliosides transport from the plasma membrane to intracellular vesicles in an ATP hydrolysis-dependent manner, thus playing a role in their internalization by endocytic retrograde transport (PMID: 33478937). ABCA13 is expressed in the human trachea, testis, and bone marrow(PMID:12697998).