Proteintech, 20755-1-AP-20ul, ADAM20 Polyclonal antibody

20755-1-AP targets ADAM20 in WB, ELISA applications and shows reactivity with human, mouse samples.
Tested Applications
Positive WB detected in: HeLa cells, PC-3 cells, mouse brain tissue
Recommended dilution
Western Blot (WB): WB : 1:500-1:1000
Background Information
ADAM20 is the functional equivalent of sperm fertilin-alpha (ADAM1), since that gene is nonfunctional in human. And northern blot analysis detected the 2.8-kb ADAM20 mRNA only in testis. The exclusive expression of ADAM20 in human testis and their sequence similarity with the fertilins suggest that it is expressed on sperm cells and involved in sperm maturation and/or fertilization(PMID:9469942). The full length protein has a singnal peptide, propeptide and 6 glycosylation sites.