Proteintech, 22526-1-AP-20ul, ABHD15 Polyclonal antibody

22526-1-AP targets ABHD15 in WB, ELISA applications and shows reactivity with human, mouse samples.
Tested Applications
Positive WB detected in: mouse lung tissue, Transfected HEK-293 cells
Recommended dilution
Western Blot (WB): WB : 1:200-1:1000
Background Information
ABHD15 belongs to the α/β-hydrolase superfamily which consists of various lipases, esterases, and proteases that share an α/β fold as a common structural feature. ABHD15 is highly expressed in adipose tissues and is required for the anti-lipolytic action of INS in white adipose tissue (WAT). ABHD15 expression is decreased in humans with obesity and diabetes compared to humans with obesity and normal glucose tolerance, identifying ABHD15 as a potential therapeutic target to mitigate INS resistance (PMID: 29768196).