Description
22660-1-AP targets ABHD12 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Applications
Positive WB detected in: mouse cerebellum tissue, rat cerebellum tissue
Recommended dilution
Western Blot (WB): WB : 1:500-1:1000
Background Information
ABHD12 is a recently identified post-genomic protein with poorly defined physiological function. Its potential role as a brain 2-AG hydrolase was revealed using ABPP with mouse brain proteome and it was estimated that at the bulk brain level. ABHD12 is a major brain lyso-PS lipase, implicating lyso-PSs in the neurological disease PHARC, which is caused by null mutations in the ABHD12 gene (PMID: 21418147, 25580854).