Proteintech, 23785-1-AP-20ul, AKNA Polyclonal antibody

23785-1-AP targets AKNA in WB, ELISA applications and shows reactivity with human samples.
Tested Applications
Positive WB detected in: K-562 cells
Recommended dilution
Western Blot (WB): WB : 1:500-1:2000
Background Information
AKNA also named as AT hook transcription factor is a 1439 amino-acids protein. AKNA, encodes a lymphoid-specific AT-hook transcription factor that is highly expressed by B and T lymphocytes. It coordinately regulates expression of the CD40 receptor and its ligand (CD154), two molecules that are critical for antigen-dependent B-cell development. AKNA expresses at least nine distinct transcripts, some of which are expressed in a tissue-specific manner. These transcripts are products of alternative splicing, alternative promoter usage, and alternative polyadenylation. The alternative AKNA transcripts are predicted to encode overlapping protein isoforms, some of which (p70 and p100) (PMID:15869410)