Proteintech, 23938-1-AP-50uL, ANK1 Polyclonal antibody

23938-1-AP targets ANK1 in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.
Background Information
Ankyrin-1 (ANK1) is also named as Ankyrin-R and Erythrocyte ankyrin. The stability and shape of the erythrocyte membrane is provided by the ankyrin-1 complex (PMID:18440852). ANK1 can attache integral membrane proteins to cytoskeletal elements. And it binds to the erythrocyte membrane protein band 4.2, to Na-K ATPase, to the lymphocyte membrane protein GP85, and to the cytoskeletal proteins fodrin, tubulin, vimentin and desmin.(PMID:12456646). This target recognizes the C-terminal of Ankyrin-1 and also recognizes ankyrin-1 isoform 5 (206 kDa). It can identify isoforms such as Er5, Er6, Er11, Er12, Er13, Er14, Er16, Mu17, Mu18, Mu19, Mu20, 22, and 23.