Proteintech, 23998-1-AP-150ul, ANKRD13A Polyclonal antibody

23998-1-AP targets ANKRD13A in WB, IP, ELISA applications and shows reactivity with human samples.
Tested Applications
Positive WB detected in: HepG2 cells, Jurkat cells, LNCaP cells
Recommended dilution
Western Blot (WB): WB : 1:2000-1:16000
Background Information
ANKRD13A, also named ANKRD13, is a 590 amino acid protein that contains two ANK repeats and four UIM (ubiquitin-interacting motif) repeats. ANKRD13A localizes in the cell membrane. ANKRD13A is an ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin, but does not bind 'Lys-48'-linked ubiquitin. ANKRD13A positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.