Proteintech, 25213-1-AP-150ul, Adropin Polyclonal antibody

25213-1-AP targets Adropin in IHC, IF/ICC, ELISA applications and shows reactivity with human samples.
Tested Applications
Positive IHC detected in: human liver tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0
Positive IF/ICC detected in: SH-SY5Y cells
Recommended dilution
Immunohistochemistry (IHC): IHC : 1:50-1:500
Immunofluorescence (IF)/ICC: IF/ICC : 1:200-1:800
Background Information
Adropin is a nutritionally regulated peptide hormone that is primarily secreted by the liver and is important in maintaining metabolic and non-metabolic homeostasis. Adropin regulates glucose and fatty acid metabolism and exerts a potential protective effect on endothelial function through modulation of endothelial nitric oxide (NO) synthesis. It is associated with obesity and is involved in the prevention of insulin resistance, dyslipidemia, and impaired glucose tolerance (PMID: 22318315).