Description
25765-1-AP targets ANKRD40 in IP, ELISA applications and shows reactivity with human samples.
Tested Applications
Positive IP detected in: MCF-7 cells
Recommended dilution
Immunoprecipitation (IP): IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
Background Information
ANKRD40 (ankyrin repeat domain 40) is a protein-coding gene conserved across mammals, including humans, mice, rats, and whales. The encoded protein contains ankyrin repeat domains, which are structural motifs typically involved in protein-protein interactions. In humans, ANKRD40 is located on chromosome 17 (17q21.33) and is ubiquitously expressed, with higher levels in tissues like the brain and adipose. ANKRD40 implicated in DNA replication, cell adhesion and migration; its expression correlates with tumor progression, yet precise molecular mechanisms remain undefined.