Description
27898-1-AP targets ACP5 in WB, ELISA applications and shows reactivity with human samples.
Tested Applications
Positive WB detected in: HepG2 cells, MCF-7 cells, SW480 cells
Recommended dilution
Western Blot (WB): WB : 1:500-1:2000
Background Information
Tartrate-resistant acid phosphatase (TRAP/ACP5) is a metalloproteinase enzyme that maps to chromosome 19p13.2 and spans approximately 3 kb, belonging to the acid phosphatase family that catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. Accumulating studies have demonstrated that ACP5 broadly participates in various malignant processes including uncontrolled proliferation, chemotherapy resistance, cellular invasion and metastasis.