Proteintech, 30713-1-AP-20ul, ADRB3 Polyclonal antibody

30713-1-AP targets ADRB3 in WB, ELISA applications and shows reactivity with Human samples.
Tested Applications
Positive WB detected in: A549 cells, MCF-7 cells
Recommended dilution
Western Blot (WB): WB : 1:1000-1:4000
Background Information
Beta-3 adrenergic receptor(ADRB3), a member of the G-protein-coupled receptor family, is expressed mainly in adipose tissue and is thought to contribute to lipolysis and thermogenesis. In addition, the overexpression of ADRB3 has been found in several cancer types, including breast cancer, gallbladder cancer , and colorectal cancer. More recently, the involvement of ADRB3 in the metabolic reprogramming of melanoma, the promotion of immune tolerance, and the regulation of cancer differentiation have been described. (PMID: 32514619)