Proteintech, 31075-1-AP-20ul, ADAMTS14 Polyclonal antibody

31075-1-AP targets ADAMTS14 in WB, ELISA applications and shows reactivity with human samples.
Tested Applications
Positive WB detected in: HL-60 cells, K-562 cells, HUVEC cells
Recommended dilution
Western Blot (WB): WB : 1:500-1:1000
Background Information
The ADAMTS (a disintegrin-like and metalloproteinase with thrombospondin motifs) is a family of extracellular metalloproteinases mediating diverse functions including matrix degradation, blood coagulation, and angiogenesis. The ADAMTS family constitutes a group of proteins composed of 19 enzymes and 7 ADAMTS-like proteins. ADAMTS14 possesses high similarity with ADAMTS2 and ADAMTS3 in sequence and domain composition (PMID: 11741898). The expression of ADAMTS14 is correlated with the occurrence and progression of colorectal cancer and oral squamous cell carcinoma (PMID: 34856162; PMID: 32102222).