Proteintech, 31483-1-AP-150ul, AGPAT2 Polyclonal antibody

31483-1-AP targets AGPAT2 in WB, ELISA applications and shows reactivity with Human samples.
Tested Applications
Positive WB detected in: L02 cells, THP-1 cells, human adipose tissue
Recommended dilution
Western Blot (WB): WB : 1:500-1:2000
Background Information
1-acyl-sn-glycerol-3-phosphate acyltransferase beta (AGPAT2) belongs to a family of enzymes catalyzing the sn-2 acylation of the glycerol-3-phosphate backbone. AGPAT2 is highly expressed in adipose tissues, liver, and skeletal muscle. AGPAT2 is the only AGPAT isoform whose loss-of-function mutations cause a severe form of human congenital generalized lipodystrophy (PMID: 34824276). Human and mouse AGPAT2 have a calculated molecular mass of 31 kDa, and an alternatively spliced form of AGPAT2 mRNA, encoding a protein of 246 rather than 278 amino acids, is also found in human (PMID: 19336658). Western detected AGPAT2 at an apparent molecular mass of 27 kDa.