Proteintech, 31542-1-AP-20ul, AKAP8 Polyclonal antibody

31542-1-AP targets AKAP8 in WB, ELISA applications and shows reactivity with Human samples.
Tested Applications
Positive WB detected in: A549 cells, HL-60 cells, HeLa cells, HepG2 cells
Recommended dilution
Western Blot (WB): WB : 1:5000-1:50000
Background Information
AKAP8 (A-kinase anchor protein 8), also called AKAP95, is a A-kinase anchor protein that directs activity of protein kinase A by tethering the enzyme near its physiologic substrates (PMID: 9473338; 10601332). It is associated with chromatin and nuclear matrix which has a remarkable activity in promoting chromatin transcription (PMID: 31980632), and it is also required for cell cycle G2/M transition and histone deacetylation during mitosis (PMID: 16980585).