Description
32990-1-AP targets ACBP/DBI in WB, ELISA applications and shows reactivity with mouse, rat samples.
Tested Applications
Positive WB detected in: mouse kidney tissue, mouse liver tissue, rat kidney tissue, rat liver tissue
Recommended dilution
Western Blot (WB): WB : 1:1000-1:6000
Background Information
Acbp/Dbi (acyl-CoA binding protein/Diazepam-binding inhibitor) is a widely expressed protein that binds long-chain fatty acyl-CoA esters and plays a role in fatty acyl-CoA transport and pool formation. Acbp/Dbi is critical to cellular proliferation, differentiation, mitochondrial functions, and autophagy. Deletion of Acbp in mouse results in sebocyte hyperplasia and sparse, matted hair with a greasy appearance (PMID: 32632162, 16902415).