Description
60485-4-Ig targets ACAT1 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Applications
Positive WB detected in: LNCaP cells, HSC-T6 cells, 4T1 cells, rabbit brain tissue, pig brain tissue, A549 cells, HepG2 cells, MJ cells, Karpas-422 cells
Recommended dilution
Western Blot (WB): WB : 1:5000-1:50000
Background Information
ACAT1 (acetyl-CoA acetyltransferase), is a mitochondrial enzyme catalyzing the reversible formation or breakdown of acetoacetyl-CoA and plays important roles in ketogenesis and ketolysis. Deficiency of ACAT1 causes an inherited metabolic disorder. Recently ACAT1 has been reported to get involved in cancer progression.