Proteintech, 66677-1-Ig-150ul, AKR7A2 Monoclonal antibody

66677-1-Ig targets AKR7A2 in WB, IHC, IF/ICC, ELISA applications and shows reactivity with Human samples.
Tested Applications
Positive WB detected in: Jurkat cells, HEK-293 cells
Positive IHC detected in: human liver cancer tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0
Positive IF/ICC detected in: HepG2 cells
Recommended dilution
Western Blot (WB): WB : 1:1000-1:6000
Immunohistochemistry (IHC): IHC : 1:150-1:600
Immunofluorescence (IF)/ICC: IF/ICC : 1:200-1:800
Background Information
AKR7A2(Aflatoxin B1 aldehyde reductase member 2) is also named as AFAR, AFAR1, AKR7 and belongs to the aldo/keto reductase family. AKR7A2 enzyme is catalytically active toward aldehydes arising from lipid peroxidation, suggesting a potential role against the consequences of oxidative stress, and representing an important detoxication route in mammalian cells(PMID:22001351).