Description
67638-1-Ig targets ANO2 in WB, IHC, IF-P, ELISA applications and shows reactivity with Human, mouse samples.
Tested Applications
Positive WB detected in: Y79 cells, NCCIT cells, U2OS cells, MDA-MB-231 cells, T-47D cells, HeLa cells
Positive IHC detected in: mouse eye tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0
Positive IF-P detected in: mouse eye tissue
Recommended dilution
Western Blot (WB): WB : 1:1000-1:6000
Immunohistochemistry (IHC): IHC : 1:50-1:500
Immunofluorescence (IF)-P: IF-P : 1:200-1:800
Background Information
ANO2, also named as C12orf3 and TMEM16B, belongs to the anoctamin family. It acts as a calcium-activated chloride channel (CaCC), mostly in photoreceptors. It may mediate olfactory amplification in olfactory sensory neurons (OSNs) and light perception amplification in retina.