Proteintech, 68396-1-Ig-100uL, ALDOB Monoclonal antibody

68396-1-Ig targets ALDOB in WB, IF/ICC, ELISA applications and shows reactivity with human, mouse, rat, rabbit samples.
Background Information
Fructose-1,6-bisphosphate aldolase is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate.Vertebrates have 3 aldolase isozymes, aldolase A (ALDOA), B (ALDOB), and C (ALDOC). Deficiency of this enzyme ALDOB causes an accumulation of fructose-1-phosphate after fructose intake, which results in toxic symptoms like vomiting, hypoglycemia, jaundice, elevated liver enzymes and hepatomegaly(PMID:22375183). This antibody specific detect ALDOB.