Proteintech, 68636-1-Ig-20ul, 1-Methyladenosine Monoclonal antibody

68636-1-Ig targets 1-Methyladenosine in Dot Blot, ELISA applications and shows reactivity with chemical compound samples.
Tested Applications
Positive Dot Blot detected in: RNA
Recommended dilution
DOT BLOT: DOT BLOT : 1:1000-1:4000
Background Information
1-Methyladenosine, also known as m1A, belongs to the class of organic compounds known as purine nucleosides. M1A is important for the tRNA 3-dimensional structure, and it is also important for structure stabilization of tRNA due to its positive electrostatic charge and assists in correct folding of tRNA. Recently evidence suggests that m1A in tRNA is under reversible regulation that is installed by a tRNA m1A methyltransferase (MTase) and is erased by AlkB Homolog 1 (ALKBH1) and AlkB Homolog 3 (ALKBH3).Protocol for Dot Blot:https://www.ptglab.com/protocol/68636-1-IgDotBlot.pdf